first open:
C:\Program Files\Team MediaPortal\MediaPortal\
is that a problem (does it exist?)
next try running "configuration.exe" form that directory
then try running "MediaPortal.exe"
if you get error as some stage there should be a "log" folder (C:\Program Files\Team MediaPortal\MediaPortal\log) containing several error logs
I suspect you may be and idiot and doing something stupid
, but just what that is?