I have the Hauppauge 45 button silver remote. When using it with MediaPortal in Windows Vista Ultimate it doesn't work properly all the time. Through trial and error I discovered that when I don't use the remote for about 15 seconds it won't work anymore. I have to restart MediaPortal to get it to work again. But then again, when I don't use it for about 15 seconds it stops responding and I have to restart Mediaportal again. I don't have this problem in other applications like JRiver Media Center or Windows Media Center.