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Nope. Here's what I did:

set ports in mpextended like you said (port 80 was 8080 by default and 4322 was already set);

tried http://127.0.0.1 which worked

tried to access web mp which does now not work anymore neither with the pure adress nor with any port addition

And what do you mean by open ports?

As I understand this I forward them and therefore I have to state which port should be forwarded by the router to which port.