I've been running with v5.6 for a couple of weeks also. Only thing i noticed is that some checkboxes (from a plugin!) wouldn't stick. If i check it, close config, open config, it's UNchecked again. Will contact plugin developer to see if it's on that side.
TvWishList plugin. Problem: the checking/unchecking of Wishes isn't saved when you close config. But not sure if it's a problem with the plugin or MySQLCan you tell me wich plugins are giving you troubles? I would like to test it aswell.