I work with the E-450 platform including DVB-C HDTV, Blu-Ray and a PicoPSU plus external power brick. However, I also wait on the "next Step" especially in terms of CPU-power. As of today, AMD made their new lines of low energy consumption processors, the A & E-Series Kabini and Temash APUs available. Perhaps the A4-5000 (TDP 15W) or the A6-5200 (TDP 25W) may bring a boost in combination with an energy efficient motherboard.
I have just been doing a good bit of reading on them, the A4-5000 sounds like it might be the best fit for power consumption (but the A4-5200 would be ok as well with my current plan to either use the same power or less). Might have to wait a few months before they are available but that works ok with my upgrade path for the 2nd half of this year. The new atom's look to be too far out at this stage to catch my eye which is a shame. Not to worry, the e350 has been a great low power setup thus far.