No. The S. drive - or any other letter you chose to assign rather than "S" - is required for MP2 to function correctly.Can this be removed or chosen not to install?
If you're just using the TV Server without the MP2 client, then it should be working without dokan. If you really want to remove the virtual drive, then you have to uninstall the Dokan library 0.5.3 (control panel -> programs and features). After that the virtual drive should not appear anymore. To completely get rid of it, you have to delete the "dokan.sys" file in windows\system32\drivers\.Does it use it even if you're just running the TV Server?
As per the first post:How do you want to use the TVServer without the client?
I've installed TV server from MP2* to use with Kodi