Depends on the TV but most are bad at upscaling, tried Sony Bravia recently and LG before that but 1080P all looked worse on than it did on a native 1080P screen which was the reason I went back to the W855B and will wait until 4K tech gets better or has more content.
So would let madVR handle the upscaling if you can offload it by the GPU or have enough resources because you have more algorithm choices which your TV lacks due to its limited hardware or just poor implementation.
It will be a new LG 65E6D. I will test it when it arrives but i tend to use MadVR